Ekadashi Fasting and Healthy Aging: A Mathematical Model

Ekadashi fasting, a biweekly practice aligned with lunar cycles, offers a unique model for studying chronobiology in healthy aging. This study develops a mathematical framework using impulsive differential equations to quantify its effects on aging biomarkers, including autophagy, mitochondrial quality, reactive oxygen species (ROS), and NAD⁺/NADH ratio. Simulations over 365 days reveal that 36-hour fasts every 14.8 days induce autophagy spikes, increase mitochondrial quality by ~22%, reduce ROS by ~18%,… Read More »Ekadashi Fasting and Healthy Aging: A Mathematical Model