Spike Protein Detoxification Protocol of Dr Peter McCullough

Spike Protein Detoxification Protocol of Dr Peter McCullough

by Jeffrey Dach MD

Mike is a 62 year old hedge fund manager who took the multiple Ĉøѷϊƌ Ѷåććĩƞēs over the past three years. He was rushed to the hospital Emergency Room with chest pain, and quickly transferred to the Cardiac Catheter Laboratory where coronary angiography failed to show the cause of his chest pain. The doctors were perplexed. In any event, a stent was placed into one of the coronary arteries which was thought to be narrowed slightly. He went home and a few weeks later had another bout of chest pain. The above scenario was repeated with a quick trip back to the Cardiac Cath Lab,  and again coronary angiogram showed very little findings. A second sent was placed anyway. He went home and a few weeks later, everything was repeated again. A third bout of chest pain sent him back to the hospital and a third stent was placed. And again, after he went home, he still complained of intermittent chest pain despite the three stents. The doctors were perplexed, and had nothing to further to offer the patient.

Header Image: Courtesy of McCullough, Peter A., et. al. “Clinical rationale for SARS-CoV-2 base spike protein detoxification in post COVID-19 and vaccine injury syndromes.” J Am Physicians Surg 28 (2023): 90-94.(1)

Mike’s story is typical for chest pain from myocarditis (inflammation of the heart muscle) induced by the Ĉøѷϊƌ Ѷåććĩƞē which causes ŝҏіке protein accumulation in the myocardium. Symptoms can include chest pain, as well as the more serious cardiac arrhythmia and sudden cardiac arrest.  Myocardial function can be compromised leading to congestive heart failure with reduced ejection fraction. Cardiologists are willfully blind to these adverse effects of the Ĉøѷϊƌ Ѷåććĩƞēs, thus the futile repeated procedures in the Cath Lab.

The Ĉøѷϊƌ Ѷåććĩƞē is not really a Ѷåććĩƞē. It is genetic therapy which programs our cells with messenger RNA which instructs our cells to manufacture the ŝҏіке protein, an extremely toxic substance which induces an inflammatory reaction.There is no way to turn off this production, There is no “Off Switch”.

A commonly reported symptom after Ĉøѷϊƌ Ѷåććĩƞation is pain and tenderness within enlarged axillary lymph nodes which may last for months. This is caused by ŝҏіке protein accumulation within axillary lymph nodes. Unfortunately, spike protein is produced and accumulates in many other organ systems because of the lipid nanoparticle delivery vehicle. Thus, the messenger RNA delivered to the body by the Ĉøѷϊƌ Ѷåććĩƞē travels freely throughout the body and is incorporated into cells of many other organ systems, the heart, brain, nervous system, and ovaries etc., accounting for the extensive varied adverse side effects.

The next obvious question is, what can be done about all this ŝҏіке protein accumulating in the heart and other organs? What can we do to get rid of it? Unfortunately conventional medicine is of no help. Mainstream cardiologists simply throw up their hands and shrug their shoulders and have nothing useful to offer.

There is one eminent, highly published cardiologist who has offered a treatment protocol which, in my opinion, is highly effective for removing ŝҏіке protein. This is the Dr. Peter McCullough’s ŝҏіке protein detoxification protocol. This is the protocol Mike should have been taking from the beginning.

Base Spike Detoxification Protocol from Dr Peter McCullough

Left Image: courtesy of McCullough, Peter A., Cade Wynn, and Brian C. Procter. “Clinical rationale for SARS-CoV-2 base spike protein detoxification in post COVID-19 and vaccine injury syndromes.” J Am Physicians Surg 28 (2023): 90-94.(1)

IN 2024, Dr Peter McCullough writes:

The spike protein is responsible for the pathogenicity of the SARS-CoV-2 infection and drives the development of adverse events, injuries, disabilities, and death after vaccination through immunologic and thrombotic mechanisms. The long-lasting spike protein has been found in the brain, heart, liver, kidneys, ovaries, testicles, and other vital organs at autopsy in cases of death after vaccination. In the case of vaccine-induced thrombotic injury, the spike protein has been found within the blood clot itself. Thus, there is strong rationale for considering residual SARS-CoV-2 spike protein as a treatment target in post COVID-19 and vaccine injury syndromes. The spike protein participates directly in pathophysiology, incites inflammation, and propels thrombosis. While specific syndromes (cardiovascular, neurological, endocrine, thrombotic, immunological) will require additional therapies, we propose the clinical rationale for a base detoxification regimen of oral nattokinase, bromelain, and curcumin for patients with post-acute sequalae from SARS-CoV-2 infection and COVID-19 vaccination. The empiric regimen can be continued for 3-12 months or more and be guided by clinical parameters:
‍
– Nattokinase 2000 FU (100) mg orally twice a day without food
– Bromelain 500 mg orally once a day without food
– Curcumin 500 mg orally twice a day (nano, liposomal, or with piperine additive suggested)

No therapeutic claims can be made for this regimen because it has not been tested in large, prospective, double-blind, placebo controlled randomized trials. No such studies are planned or funded currently by federal or institutional sponsors. The main caveats are bleeding and allergic reactions. The regimen can be used in addition to anti-platelet and antithrombotic agents, however, caution is advised with respect to monitoring bleeding risks. (1)

How to Order Supplements On-Line

Nattokinase, Bromelain and Curcumin are nutritional supplements which can be purchased over the counter without a prescription. For your convenience, here are links to these products at my Pure Encapsulations Store for on-line ordering:

NSK-SD (Nattokinase) – each vegetable capsule contains: nattokinase (2000 FU) (soy) 100 mg

Nattokinase is a highly purified fibrinolytic enzyme that has demonstrated encouraging potential for supporting endogenous fibrinolytic activity and promoting healthy blood flow, circulation, and blood vessel function. Pure Encapsulations NSK- SD is standardized to contain a minimum of 20,000 FU (fibrinolytic units) per gram.

Bromelain 2400  Each vegetable capsule contains Bromelain (2,400 gdu/gram) 500 mg
Bromelain enhances digestion and maintains healthy musculoskeletal tissue. Bromelain is a proteolytic enzyme from the stem of the pineapple plant. Taken with food, bromelain aids in the healthy functioning of the digestive system. Taken between meals, bromelain maintains healthy kinin and fibrin production, supporting healthy musculoskeletal function. Bromelain 2400 nutritionally supports the body’s innate ability to digest food and to maintain musculoskeletal comfort at the cellular level.

Curcumin 500 with Bioperine® : each vegetable capsules contains:turmeric (Curcuma longa) extract (root)† (standardized to contain 95% curcuminoids) 500 mg. – Bioperine® (Piper nigrum) extract (fruit) †† 5.3 mg. Turmeric may be contra-indicated with blood thinning medications.

Curcumin 500 with Bioperine® provides powerful support for maintaining a healthy inflammatory response, promoting cellular health, and supporting healthy liver, colon and musculoskeletal function. Bioperine® is a black pepper extract that contains the alkaloid piperine. Research reveals that it has the potential to enhance the bioavailability of curcumin, promoting its absorption.

Empiric Therapy can be Pursued

In April 2024, Dr Frank Yap, M.D. discussed the lack of clinical trials for spike protein detoxification protocols. However Dr Frank Yap feels that empiric therapy can be pursued, writing:

Patients should push their doctors to refer them to clinical trials, and when that is not feasible, then empiric therapy can be pursued. It is important to realize that in the absence of completed large randomized placebo controlled randomized trials, which are easily 5 or more years away in the future, no therapeutic claims can be made. In the meantime we must be perceptive as patients and open-minded as clinicians to come up with reasonable approaches that can be used to help those sick now with post-COVID syndromes. (9)

Conclusion: Fibrinolytic and proteolytic enzymes have a long history of use in medicine. Spike protein detoxification is one of the more recent uses. Curcumin is a well known and popular anti-inflammatory supplement used for centuries. Thanks to Dr. Peter McCullough for making this spike protein detoxification protocol available for public use. Who should be taking this? Some doctors have suggested that everyone should be taking this protocol on a regular basis. This protocol is used on an empiric basis, as there are no validating long term medical studies as yet, and probably never will be.

Although nutritional supplements in this spike protein detoxification protocol are generally regarded as safe (GRAS), the reader is advised to consult and work closely with a knowledgeable physician before starting. (1-10)

The reader is advised to read this DISCLAIMER.

Jeffrey Dach MD
7450 Griffin Road Suite 180/190
Davie, Florida 33314
954-792-4663

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Articles with related interest:

Fibrinolytic and Proteolytic Enzymes for Treatment of Various Conditions

References

ŝҏіке protein detoxification

1) McCullough, Peter A., Cade Wynn, and Brian C. Procter. “Clinical rationale for SARS-CoV-2 base spike protein detoxification in post COVID-19 and vaccine injury syndromes.” J Am Physicians Surg 28 (2023): 90-94.

2) Hulscher, Nicolas, et al. “Clinical approach to post-acute sequelae after COVID-19 infection and vaccination.” Cureus 15.11 (2023).

3) Kyriakopoulos, Anthony M., and Stephanie Seneff. “Proteolytic targets for SARS-CoV-2 spike protein degradation: Hope for systemic detoxification.” Journal of American Physicians and Surgeons 28.3 (2023): 86-93.

4) Halma, Matthew TJ, et al. “Strategies for the management of spike protein-related pathology.” Microorganisms 11.5 (2023): 1308.

5) Dhuli, K., et al. “Presence of viral spike protein and vaccinal spike protein in the blood serum of patients with long-COVID syndrome.” Eur Rev Med Pharmacol Sci 27.6 Suppl (2023): 13-19.

6) Craddock, Vaughn, et al. “Persistent circulation of soluble and extracellular vesicle‐linked Spike protein in individuals with postacute sequelae of COVID‐19.” Journal of Medical Virology 95.2 (2023): e28568.

7) Theoharides, Theoharis C. “Could SARS-CoV-2 spike protein be responsible for long-COVID syndrome?.” Molecular Neurobiology 59.3 (2022): 1850-1861.

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8) Solving the covid challenge. Base Spike Detoxification Protocol by Dr. Peter McCullough

The spike protein is responsible for the pathogenicity of the SARS-CoV-2 infection and drives the development of adverse events, injuries, disabilities, and death after vaccination through immunologic and thrombotic mechanisms. The long-lasting spike protein has been found in the brain, heart, liver, kidneys, ovaries, testicles, and other vital organs at autopsy in cases of death after vaccination. In the case of vaccine-induced thrombotic injury, the spike protein has been found within the blood clot itself. Thus, there is strong rationale for considering residual SARS-CoV-2 spike protein as a treatment target in post COVID-19 and vaccine injury syndromes. The spike protein participates directly in pathophysiology, incites inflammation, and propels thrombosis. While specific syndromes (cardiovascular, neurological, endocrine, thrombotic, immunological) will require additional therapies, we propose the clinical rationale for a base detoxification regimen of oral nattokinase, bromelain, and curcumin for patients with post-acute sequalae from SARS-CoV-2 infection and COVID-19 vaccination.

The empiric regimen can be continued for 3-12 months or more and be guided by clinical parameters:
‍
– Nattokinase 2000 FU (100) mg orally twice a day without food
– Bromelain 500 mg orally once a day without food
– Curcumin 500 mg orally twice a day (nano, liposomal, or with piperine additive suggested)

9) Dr Peter McCullough: How to Detox Spike Protein from Body
By Dr Frank Yap, M.D. – April 23, 2024

According to Dr Peter McCullough (in a Twitter post – July 2023):
Base Spike Detox is what I am currently using in my practice for those who have had COVID-19 multiple times, one or more of the COVID-19 vaccines, or both and believe persistent SARS-CoV-2 Spike protein could be causing problems in their body. A major publication is under review and editing; however, the information is far too important to hold back.

Update (Nov 2023): Published on August 25, 2023 in Journal of American Physicians and Surgeons. CLICK HERE FOR THE COMPLETE PAPER > Base Spike Protein Detoxification and on November 21, 2023 in Cureus (PubMed – November 2023)

I have arrived, based on the emerging scientific literature and my clinical observation, that three OTC products are essential as a triple base combination:

Nattokinase 2000 FU (100 mg) twice a day
Bromelain 500 mg once a day
Nano/Liposomal Curcumin 500 mg twice a day

Additional products can be added, including NAC, IVM (Ivermectin), HCQ (Hydroxychloroquine), fluvoxamine, low-dose naltrexone, and blood thinners, depending on the clinical evaluation and the syndrome. The therapeutic objective is to start treatment and allow the body to clear Spike and its fragments with the natural reticuloendothelial system. I believe this triple combination is the best approach.

Patients can get a big head start if they self-initiate Base Spike Detox as they get organized for appointments. I have found three months is a minimum duration, and some require more than a year. Don’t expect instant results, be patient. I have a major manuscript under review for publication that summarizes the clinical rationale and evidence supporting Base Spike Detox.

Important safety warnings include bleeding for those on blood thinners or who have bleeding disorders (e.g., hemophilia), soy allergy, allergies to any component of the combination, and gastrointestinal intolerance. Women of childbearing potential without contraception, pregnant, breastfeeding, and children should not take this combination unless directed by a doctor.

COVID-19 Vaccine Myocarditis Research Wins Award
We’re thrilled to announce that Dr Peter McCullough, won first place on Preprints.org for a study he co-authored on vaccine-induced myocarditis.

Preprints.org is a vital platform for the early dissemination of scholarly research before standard peer review and publication in scientific journals. By allowing research findings to be shared early with the scientific community, Preprints.org facilitates scientific communication and collaboration, enabling researchers to receive feedback and engage with the broader scientific community.

Autopsy Proven Fatal COVID-19 Vaccine-Induced Myocarditis claimed the top spot in the Medicine and Pharmacology category, specifically focusing on cardiac and cardiovascular systems. This research paper delves into a critical issue surrounding COVID-19 vaccination — the potential risk of myocarditis, particularly in cases where it leads to fatal outcomes.

Nattokinase and Spike Protein
Tanikawa et al. examined the effect of nattokinase on the spike protein of SARS-CoV-2. In the first experiment, they demonstrated that spike was degraded in a time and dose-dependent manner in a cell lysate preparation that could be analogous to a vaccine recipient. The second experiment demonstrated that nattokinase degraded the spike protein in SARS-CoV-2 infected cells. This was reproduced in a similar study done by Oba and colleagues in 2021.

Tanikawa T, Kiba Y, Yu J, Hsu K, Chen S, Ishii A, Yokogawa T, Suzuki R, Inoue Y, Kitamura M. Degradative Effect of Nattokinase on Spike Protein of SARS-CoV-2. Molecules. 2022 Aug 24;27(17):5405.

Nattokinase is dosed in fibrinolytic units (FU) per gram and can vary according to purity. Kurosawa and colleagues have shown in humans that after a single oral dose of 2000 FU D-dimer concentrations at six, and eight hours, and blood fibrin/fibrinogen degradation products at four hours after administration elevated significantly (p 

Thus an empiric starting dose could be 2000 FU twice a day. Full pharmacokinetic and pharmacodynamic studies have not been completed, but several years of market use as an over-the-counter supplement suggests nattokinase is safe with the main caveat being excessive bleeding and cautions with concurrent antiplatelet and anticoagulant drugs.

Editor’s Note: We are aware of a fact-check article by AFP titled “Experts rubbish Covid vaccine ‘detoxification’ supplement”. In my humble opinion, the title may come across as excessively confident and strongly worded.

The article makes a claim that ‘There is no evidence that nattokinase dissolves the spike protein of SARS-CoV-2 in the human body,’ while also citing evidence from the Tanikawa study. It’s important to acknowledge that the Tanikawa study is a small lab study, which is a common starting point in the research process before moving on to larger studies.

Nevertheless, we agree that nattokinase is not a miracle drug, and further research is necessary. It’s worth noting that there are more than 200 studies related to nattokinase published on PubMed.

Moreover, it’s essential to recognize that there are multiple approaches to managing COVID-19. We encourage you to consult with your trusted healthcare provider to thoroughly discuss and assess the potential benefits and risks of various possible treatments.

Ivermectin and Spike Protein
Former NIH researcher David Scheim, PhD, early in the pandemic proposed that SARS-CoV-2 Spike protein was acting like a grappling hook pulling together circulating red blood cells (RBCs) into long chains and clumps in a process called hemagglutination (HA).

This explained why the red blood cells could not carry oxygen normally and was congruent with the finding of micro blood clots in the lungs. Boschi et al have provided additional support for this mechanism (source). By reversing the clumping of red blood cells, ivermectin enabled the patient’s proper respiratory function to return.

According to the authors:

“Ivermectin blocked HemAgglutination when added to RBCs prior to spike protein and reversed HA when added afterwards.”

In another spectacular publication, Stone et al, describes the prompt improvement of oxygenation in patients with ivermectin (source).

The published oxygenation curves from multiple studies clearly show this physiological effect of ivermectin occurs so rapidly, it must be explained by a direct anti-Spike protein effect of ivermectin. An anonymous video of a critically ill man demonstrates the very effect that Scheim, Stone, Hazan, and Babalola have described in the Figure above. So for the next critically ill patient with COVID-19, if the opportunity presents itself, push for the administration of ivermectin. This is the only published therapy for COVID-19 that improves oxygen saturation while the patient mounts a recovery. As in this man, it may be the critical factor for a turnaround and a chance to walk out of the hospital.

Key Takeaway
Patients should push their doctors to refer them to clinical trials, and when that is not feasible, then empiric therapy can be pursued. It is important to realize that in the absence of completed large randomized placebo controlled randomized trials, which are easily 5 or more years away in the future, no therapeutic claims can be made. In the meantime we must be perceptive as patients and open-minded as clinicians to come up with reasonable approaches that can be used to help those sick now with post-COVID syndromes.

References:
10) Halma, M.T.J.; Plothe, C.; Marik, P.; Lawrie, T.A. Strategies for the Management of Spike Protein-Related Pathology. Microorganisms 2023, 11, 1308. https://doi.org/10.3390/microorganism...

11) Tanikawa T, Kiba Y, Yu J, Hsu K, Chen S, Ishii A, Yokogawa T, Suzuki R, Inoue Y, Kitamura M. Degradative Effect of Nattokinase on Spike Protein of SARS-CoV-2. Molecules. 2022 Aug 24;27(17):5405. doi: 10.3390/molecules27175405. PMID: 36080170; PMCID: PMC9458005.

62% Normalization in SpO2 within 24 Hours for severe COVID-19 patients after Ivermectin-Based Combination Treatment.

Peter A. McCullough’s Substack.

Editor’s Note:
Why should you trust this article? While we don’t ask for blind trust, we do encourage you to trust in your own judgment. Our primary goal is to empower you to conduct thorough research and make informed healthcare decisions in consultation with your trusted medical doctor.

Though there are many spike protein detox treatment protocols out there, we consider and recommend the I-Recover protocol as one of the best.

Given the lack of clinical trials of long-haul COVID-19 syndrome, these recommendations are based on the abnormal changes within the body associated with the COVID-19 disease and post viral illnesses along with the collective experience of FLCCC members.

This protocol has also been used to treat post-vaccine inflammatory syndromes with similar success. As with all FLCCC Alliance protocols, the components, doses, and durations will evolve as more clinical data accumulates.

Due to the marked overlap between long COVID and post-vaccine syndrome, please refer to the I-RECOVER Post-Vaccine Treatment protocol for detailed treatment strategies.

This base spike protein detox protocol consists of these three powerful ingredients: Spike Support’s Nattokinase, Bromelain, and Tumeric Extract.

Vaccinated or not, prioritizing your well-being has never been more crucial.

Buy this ultimate detox bundle today, researched by Dr. Peter McCullough.

Recommended to maintain daily health for anyone exposed to COVID, vaccines, or shedding – and may help your body repair itself and remain at optimal health.

Where to buy Base Spike Detox Trio Formula: Available on The Wellness Company’s website. Here is the link: Base Spike Detox Trio

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Jeffrey Dach MD
7450 Griffin Road, Suite 190
Davie, Fl 33314
954-792-4663

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Published on April 28th, 2024 by Jeffrey Dach MD

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