What Should Be the Cut-Off Total Testosterone Blood Level for Men with Diabetes?

Diabetes mellitus is a common chronic disease, affecting 0.5–2% worldwide. The Massachusetts Male Aging Study reported that up to 75% of men with diabetes have a lifetime risk of developing ED. Type 2 diabetes is associated with low total serum testosterone (TT) identified in several cross-sectional studies and systemic analyses. There is a lack of consensus regarding what constitutes the lowest level of testosterone within the boundaries of normality.


This study proposes a cut-off value of 403.5 ng/dl of TT blood levels as an indicator for initiation of testosterone replacement therapy in diabetic men with ED.
What Should Be the Cut-Off Total Testosterone Blood Level for Men with Diabetes?