The universe is fundamentally off kilter?

But what’s “kilter”:

This idea that, on the grandest scales, the cosmos looks largely the same regardless of position or direction is called the cosmological principle, and it underpins our best theory of how the universe evolved. For cosmologists, it is gospel. But some heretics are now calling the principle into question, pointing to fresh evidence that even at its largest scales, the cosmos is not only lumpy, but fundamentally off-kilter.

Thomas Lewton, “Controversial claim that the universe is skewed could upend cosmology” at New Scientist (April 27, 2022)

Why isn’t “kilter” whatever the universe is?

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