Artificial Intelligence in 2022 | Is Protein Folding Our Most Important Achievement?
Artificial Intelligence in 2022 | Is Protein Folding Our Most Important Achievement?
Part 2
Vicar Sayeedi
January 29, 2022
Over the past five years, rapid advances in Artificial Intelligence have been applied to solve many interesting, real-world problems. From applications in education and health, to radiology and social media, to natural language processing and speech synthesis, to lethal autonomous weapons systems, weather prediction and robotic surgery, and so much more, AI is accelerating progress across countless disciplines to a very impressive degree. But there is a consensus coalescing within the AI Thought Leader Community that recent advances in the application of AI in the complex and esoteric field of Structural Biology, specifically in the area of Protein Folding, may be AI’s greatest achievement to date. Protein Folding refers to the three-dimensional shape assumed by a protein before it begins life as a nanomachine in the human body. We’ll come back to this in just a minute.
DeepMind, a London firm acquired by Google in 2014, is perhaps the world’s preeminent AI company. On November 30, 2020, the firm published an article in the journal, ‘Nature’ confirming that they’d solved the previously insurmountable 50-year-old Protein Folding problem using a proprietary Deep Learning AI Agent known as AlphaFold. It was a shocking development that upended the world of Structural Biology. The implications of the publication were unprecedented, and they continue to reverberate across many disciplines today.
For the past fifty years, scientists have endlessly toiled over the Protein Folding problem in a never-ending struggle to understand the three-dimensional structure of protein nanomachines. It has been the grand challenge in Biology. In order to understand the final structure of proteins, scientists needed to make the protein production factory, the ribosome, express a sufficient quantity of a particular protein and then harness them before cajoling them to crystalize. This proved to be extremely challenging. If they succeeded in crystalizing a sufficient volume of these folded proteins, they could then use Xray Crystallography to better see and understand the folded structure. But it was common for this process to take years and sometimes even longer. In fact, many scientists have spent their entire careers and lives attempting to find the folded structures of various proteins. It would be far better if we could simply predict the three-dimensional Protein Folding structure by simply examining the string of amino acids involved.
At this point, most readers will undoubtedly be wondering why the three-dimensional shapes of these proteins are so important. Before we answer this question, let’s spend a minute to shape our understanding of what proteins are, how they’re made and what they do inside our bodies. Ribosomes are factories within our cells where twenty distinct amino acids are produced. Strings of these amino acids are linked together in unique ways to form proteins and then within a few milliseconds, physics intervenes to direct the final three-dimensional shape of the newly formed protein. There are twenty thousand distinct proteins in our bodies and each one folds into a distinct shape and thus has a different function. [Thus far, in nature we have identified approximately 100 million proteins.] These proteins can fold into 10 to the power 300 distinct three-dimensional structures [for reference, there are ten to the power eighty atoms in the known universe] and so, for all intents and purposes, this represents an infinite number of potential folded structures. Once folded, these proteins perform mechanical and chemical functions within cells throughout our bodies. Common proteins include hemoglobin which transports oxygen within red blood cells and insulin which metabolizes glucose.
In pharmacology, the three-dimensional folding pattern of a protein is crucial information. Once pharmaceutical scientists understand the folding pattern of a protein, they can design a chemical compound that can optimally bind itself to the protein in question in a very specific manner. This process, in effect, alters the protein’s function or disables it, thus preventing or intervening in potential pathology. So, we can see that rapidly understanding the pattern of Protein Folding is crucial in developing new prophylaxes and therapies. This is a revolutionary advancement that is expected to dramatically reduce the time required for the development of new drugs.
AlphaFold’s ability to accurately and rapidly predict Protein Folding structures is now improving our understanding of how to break down the plastics polluting our oceans, as well. These plastics are currently being deposited in our oceans at the rate of 10 million metric tons per year and with time they break into ever smaller parts due to sun and water erosion. They eventually turn into microplastics that are then ingested by marine life. Through this process, microplastics enter the food chain and so they are eventually consumed by humans. This of course can have impacts on human health that are not yet understood. AlphaFold’s ability to understand the three-dimensional shape of enzymes that are effective in breaking down plastics into their basic chemical components promises to have a great impact before these plastics can do further damage to marine ecosystems and eventually human life.
Vicar Sayeedi is a Computer Scientist and Bell Labs Alumnus, a Lecturer and a Consultant. He is also the author of several books. His most recent book is about Artificial Intelligence and is titled, The Génome Affair.
Vicar has lectured widely about Artificial Intelligence. He has recently lectured in New York at the National Hemophilia Foundation about AI & the Life Sciences. He has also lectured in London in the Royal Boroughs of Kensington & Chelsea and Westminster, in Sunnyvale in Silicon Valley, the National Library of Singapore as well as in Düsseldorf [with invitations extended to Amsterdam, Berlin, Cologne, Rome, Stockholm & Vienna] on AI and its implications for individuals and societies. Vicar has lectured at leading companies, as well. In April 2022, Vicar will be lecturing at Cambridge Library adjacent to Harvard Square.
Vicar is most interested in the big questions facing humankind. He is particularly focused on studying at the confluence of the five great disciplines of Human History, Political Science and Thought, International Affairs, Science and Technology. For geopolitical technologists, the symbiosis at this intersection offers a deep understanding and pedagogically important lessons of how advances in human endeavor have influenced and impacted civilization.
Vicar has been writing books, essays and poetry for many years. For the past 30 years, Vicar has worked in the Technology and Pharmaceutical industries. He is currently a Consultant in the Life Sciences Industry and lives in suburban Chicago with his wife and their three grown children.
You can find Vicar’s recent book on AI, The Génome Affair on Amazon at this link:
https://www.amazon.com/dp/B07YQ7M9Q7
The most recent episodes of Vicar’s ai & u! Podcast are on YouTube at the following links:
Episode 1 - https://youtu.be/yNYr28jtY_k
What is Artificial Intelligence? What is Human Intelligence?
Episode 2 - https://youtu.be/kAEgDNh1Nwc
How Did We Get Here? Machine Learning, Neural Networks & the AI Lexicon, Exciting AI Agents
Episode 3 - https://youtu.be/3PYCyv1pCgM
Deep Mind - How Powerful is Narrow AI? State Surveillance and Surveillance Capitalism
Episode 4 - https://youtu.be/WvobCMIM_H4
Impact on Societies That Possess Artificial Intelligence Versus Those that Do Not!
Episode 5 - https://youtu.be/4JVpvm4g79g
Surveillance Capitalism, Surveillance State, 4th Industrial Revolution, Bifurcation of Sapiens
Episode 6 - https://youtu.be/e1q2GgcWQok
AI, Blockchain & Quantum Computing - Implications for Global and National Governance
Episode 7 - https://youtu.be/4bDSUvrOdd4
Popular Perceptions of Intelligence, the Seat of Human Intelligence and Implications for AI
Episode 8 - https://youtu.be/3GjHqQZL7Pk
AI - Why Should I care? Plus Exciting Updates from Elon Musk and Neuralink!
Episode 9 - https://youtu.be/enpecqDecC8
AI - Excellence, Innovation & Genius
Episode 10 - https://youtu.be/UsriESlTjdA
Implications for AI as China and the West Decouple
Episode 11 - https://youtu.be/0CpaMb-yw3g
Artificial Intelligence: Ethics, Law & Society
Episode 12 - https://youtu.be/PLzodrLWMq0
AI & Lethal Autonomous Weapons Systems
Episode 13 - https://youtu.be/Lm_nrNyJRbA
AI & the Future of Work in Industry 4.0 – the 4th Industrial Revolution
Episode 14 - https://youtu.be/_3E1Mhr_Dt8
Artificial Intelligence and its Implications for Authoritarianism and Democracy
Episode 15 - https://youtu.be/IpMUqHOEd7w
Artificial Intelligence, Consciousness & the Future of Homo Sapiens
Episode 16 - https://youtu.be/mIf7_VMzGKo
AI and its Implications for America's Political Environment
Episode 17 - https://youtu.be/gsMRPnovZGI
Special Episode: Reading From The Génome Affair
Episode 18 - https://youtu.be/UxNxtWDCREM
Artificial Intelligence - Digital Tyranny, Datocracy and the Imitation Game
Episode 19 - https://youtu.be/Db8U0QQWWuY
Does Artificial Intelligence Really Replicate Human Intelligence?
Episode 20 - https://youtu.be/Np18AEq-6DM
AI & Rising Geopolitical Tensions Between China & The West
Episode 21 - https://youtu.be/fOMSvNiixA0
AI & In-vitro Fertilization [IVF]
Episode 22 - https://youtu.be/EQPpRhIV6Kw
AI & Human Intelligence: A Complex Relationship
Episode 23 - https://youtu.be/EAbQ7stY7JQ
AI Upends the World of Structural Biology
Episode 24 - https://youtu.be/Bsb1F8uoBpA
AI & COVID-19: An Extraordinary Contribution
Episode 25 - https://youtu.be/PqL5PCRc8tA
AI, Connectomics & Transhumanism: the Future of Humankind
Episode 26 - https://youtu.be/HI8Zjl8VM8U
Dramatic Upheaval Inside Google's Ethical AI Team
Episode 27 - https://youtu.be/TqWwJYc2GxQ
AI & Cyber Espionage | How Will the Sunburst Attack Affect Our Security?
Episode 28 - https://youtu.be/89BcThqgcfQ
AI & the Rapidly Escalating Threat from Deep Fake Videos
Episode 29 - https://youtu.be/zvOHRMmJNB4
AI, Facial Recognition Technology & The Digital Surveillance State
Episode 30 - https://youtu.be/br4ygfEWdk0
AI & Social Media | The Most Destructive AI We've Ever Seen?
Episode 31 - https://youtu.be/sOy12ii8zwM
The Democratization of AI & The 2021 Maiflower Expedition | Plymouth, England to Plymouth, MA
Episode 32 - https://youtu.be/bixdLL74reE
Sino-American Cold War | A Blessing in Disguise for America?
Episode 33 - https://youtu.be/tTRm312DgMc
AI & the Tyranny of Meritocracy
Episode 34 - https://youtu.be/FpPzC5VP6GM
In the Midst of Chaos and Pandemic | A Big AI Announcement From the Trump Administration
Episode 35 - https://youtu.be/bK3xCBwrG8w
Artificial Super Intelligence – Can We Control It?
Episode 36 - https://youtu.be/Rc60DQ0L86Q
A New America | Hope with a Big Dose of Caution
Episode 37 - https://youtu.be/UBenYYHbYqM
Will AI [Science & Tech] Benefit From a New Cold War with China?
Episode 38 - https://youtu.be/JewJnPywnOU
Will AI Eventually Replace All Other Forms of Government?
Episode 39 - https://youtu.be/ibuJ8vozyqg
Will AI Perpetuate Bias in Employment, Health Systems, Law and Society?
Episode 40 - https://youtu.be/IJYbPfGC-08
AI | Will it be the Bain of Cyber Criminals?
Episode 41 - https://youtu.be/ozrO5_XTYKQ
AI | What Will it Mean for the Future of Work?
Episode 42 - https://youtu.be/kDKapDK-Vb0
AI | A Harbinger for the End of Democracy?
Episode 43 - https://youtu.be/7XeNyE8CA9I
AI & the Life Sciences | Developments in Connectomics & Radiology
Episode 44 - https://youtu.be/mWaPW_UolVo
AI & Geopolitics | Critical Strategic Planning in the Age of China
Episode 45 - https://youtu.be/qOSOc3vJRBk
AI & Humankind | What Might the Future Hold?
Episode 46 - https://youtu.be/atMSV1WAFkg
AI Enabled Surveillance | An Important Tool to Contain Dangerous Personality Traits?
Episode 47 - https://youtu.be/kz7-EDmlGXc
Will AI Favor Authoritarianism or Democracy?
Episode 48 - https://youtu.be/uTvKWQgdOaI
AI | A Key Enabler of Universal Basic Income?
Episode 49 - https://youtu.be/sy48Xqo-3qM
AI & The Future of Government, Industry, Markets &Trade
Episode 50 - https://youtu.be/JU1oGzb5TS0
AI & Surveillance | America’s New Strategy in the Middle East
Episode 51 - https://youtu.be/nOCQjUxLWJY
AI-Enabled Global Government | An Idea Whose Time Has Come?
Episode 52 - https://youtu.be/g1VJqiI3HyE
AI & Healthcare | What Will the Future Look Like? Will it be More Equitable?
Episode 53 - https://youtu.be/ie9KAg_kF7Q
AI & Surveillance | The Ethical Dilemma of Facial Recognition Software
Episode 54 - https://youtu.be/ie9KAg_kF7Q
AI & Regulation | Europe is Leading the Way
Episode 55 - https://youtu.be/l-gcYTZMsm8
AI & Consciousness | Will Machines Soon be Sentient?
Episode 56 - https://youtu.be/-8BaouCn9cs
AI & Regulation | Europe Announces New Rules
Episode 57 - https://youtu.be/243zm7aHImQ
AI & Human Emotion Recognition | Is it Inherently Flawed?
Episode 58 - https://youtu.be/rdXllGj8rbo
AI & Autonomous Vehicles | Where are We Now?
Episode 59 - https://youtu.be/EMbqpN5mbqw
AI & the 4 Little Trees | More on Emotion Recognition
Episode 60 - https://youtu.be/K5wtkj-VTrk
AI & the Colonial Pipeline Attack | Cyber Threats are Growing Rapidly
Episode 61 - https://youtu.be/03KysO3VJgI
AI & the Coronavirus | A Postmortem
Episode 62 - https://youtu.be/7wmSIWgbuQI
AI on the Battlefield | The Conflict in Gaza
Episode 63 - https://youtu.be/a_1AmLJD3lo
AI and Xenophobia | Will We Finally Break the Cycle?
Episode 64 - https://youtu.be/9s-Go1TYK9c
AI, Cyber Attacks & the Future of War | Where are We Headed?
Episode 65 - https://youtu.be/1nKbTMzfpqM
Artificial Intelligence | Humankind’s Final and Greatest Invention
Episode 66 - https://youtu.be/cplR62KTa88
America & the 4th Industrial Revolution | Where do We Go from Here?
Episode 67 - https://youtu.be/RMrqreI-PRw
Artificial Intelligence | [Digital] Life After Death
Episode 68 - https://youtu.be/KzR8NkVdT0Q
Artificial Intelligence | The Fear Factor
Episode 69 - https://youtu.be/BI0HqACc4Ek
Artificial Intelligence | The Trust Factor
Episode 70 - https://youtu.be/nKhqVtQC_NI
Artificial Intelligence | Implications for the Future of Democracy
Episode 71 - https://youtu.be/GKD5hXmnpTU
Artificial Intelligence | Deep Fakes & Pornography
Episode 72 - https://youtu.be/KJdoBm5Kmw8
Artificial Intelligence | Working in the 21st Century
Episode 73 - https://youtu.be/lLY6gF_eeas
AI & Disinformation | Implications for Democracy & Geopolitics
Episode 74 - https://youtu.be/URsauWURj5A
AI, Climate Change & Pandemics | A Case for Global Governance?
Episode 75 - https://youtu.be/cu7xOHpNiO4
Artificial Intelligence | New Year’s Resolutions & Societal Reformation
Episode 76 - https://youtu.be/1-orEsKg5fM
Artificial Intelligence | Meritocracy and the Gathering Storm
Episode 77 - https://youtu.be/jYzyrxhxCJk
AI, Authoritarianism & Democracy | What Does the Future Hold?
Episode 78 – https://youtu.be/G5dlaB8TZJQ
AI & Speciation | Symbiosis and the 4th Industrial Revolution
Episode 79 – https://youtu.be/8pq2ZAxRdcY
AI and Disinformation | Echo Chambers in an Age of Division
Episode 80 – https://youtu.be/bewLnveVpDI
AI & Human Conflict | Objectivism, Tribalism & the Dunning-Kruger Effect
Episode 81 – https://youtu.be/Z5ZvMYuNhLQ
AI, Climate Change & Migration | Sowing the Seeds of Intraplanetary Discord
Episode 82 – https://youtu.be/mP-r_0pS3P8
Artificial Intelligence in 2022 | Where are We Now and What Does the Future Hold?
Episode 83 – https://youtu.be/vYSW-pceOQE
Artificial Intelligence in 2022 | Is Protein Folding Our Most Important Achievement?
Part 2
Vicar Sayeedi
January 29, 2022
Over the past five years, rapid advances in Artificial Intelligence have been applied to solve many interesting, real-world problems. From applications in education and health, to radiology and social media, to natural language processing and speech synthesis, to lethal autonomous weapons systems, weather prediction and robotic surgery, and so much more, AI is accelerating progress across countless disciplines to a very impressive degree. But there is a consensus coalescing within the AI Thought Leader Community that recent advances in the application of AI in the complex and esoteric field of Structural Biology, specifically in the area of Protein Folding, may be AI’s greatest achievement to date. Protein Folding refers to the three-dimensional shape assumed by a protein before it begins life as a nanomachine in the human body. We’ll come back to this in just a minute.
DeepMind, a London firm acquired by Google in 2014, is perhaps the world’s preeminent AI company. On November 30, 2020, the firm published an article in the journal, ‘Nature’ confirming that they’d solved the previously insurmountable 50-year-old Protein Folding problem using a proprietary Deep Learning AI Agent known as AlphaFold. It was a shocking development that upended the world of Structural Biology. The implications of the publication were unprecedented, and they continue to reverberate across many disciplines today.
For the past fifty years, scientists have endlessly toiled over the Protein Folding problem in a never-ending struggle to understand the three-dimensional structure of protein nanomachines. It has been the grand challenge in Biology. In order to understand the final structure of proteins, scientists needed to make the protein production factory, the ribosome, express a sufficient quantity of a particular protein and then harness them before cajoling them to crystalize. This proved to be extremely challenging. If they succeeded in crystalizing a sufficient volume of these folded proteins, they could then use Xray Crystallography to better see and understand the folded structure. But it was common for this process to take years and sometimes even longer. In fact, many scientists have spent their entire careers and lives attempting to find the folded structures of various proteins. It would be far better if we could simply predict the three-dimensional Protein Folding structure by simply examining the string of amino acids involved.
At this point, most readers will undoubtedly be wondering why the three-dimensional shapes of these proteins are so important. Before we answer this question, let’s spend a minute to shape our understanding of what proteins are, how they’re made and what they do inside our bodies. Ribosomes are factories within our cells where twenty distinct amino acids are produced. Strings of these amino acids are linked together in unique ways to form proteins and then within a few milliseconds, physics intervenes to direct the final three-dimensional shape of the newly formed protein. There are twenty thousand distinct proteins in our bodies and each one folds into a distinct shape and thus has a different function. [Thus far, in nature we have identified approximately 100 million proteins.] These proteins can fold into 10 to the power 300 distinct three-dimensional structures [for reference, there are ten to the power eighty atoms in the known universe] and so, for all intents and purposes, this represents an infinite number of potential folded structures. Once folded, these proteins perform mechanical and chemical functions within cells throughout our bodies. Common proteins include hemoglobin which transports oxygen within red blood cells and insulin which metabolizes glucose.
In pharmacology, the three-dimensional folding pattern of a protein is crucial information. Once pharmaceutical scientists understand the folding pattern of a protein, they can design a chemical compound that can optimally bind itself to the protein in question in a very specific manner. This process, in effect, alters the protein’s function or disables it, thus preventing or intervening in potential pathology. So, we can see that rapidly understanding the pattern of Protein Folding is crucial in developing new prophylaxes and therapies. This is a revolutionary advancement that is expected to dramatically reduce the time required for the development of new drugs.
AlphaFold’s ability to accurately and rapidly predict Protein Folding structures is now improving our understanding of how to break down the plastics polluting our oceans, as well. These plastics are currently being deposited in our oceans at the rate of 10 million metric tons per year and with time they break into ever smaller parts due to sun and water erosion. They eventually turn into microplastics that are then ingested by marine life. Through this process, microplastics enter the food chain and so they are eventually consumed by humans. This of course can have impacts on human health that are not yet understood. AlphaFold’s ability to understand the three-dimensional shape of enzymes that are effective in breaking down plastics into their basic chemical components promises to have a great impact before these plastics can do further damage to marine ecosystems and eventually human life.
Vicar Sayeedi is a Computer Scientist and Bell Labs Alumnus, a Lecturer and a Consultant. He is also the author of several books. His most recent book is about Artificial Intelligence and is titled, The Génome Affair.
Vicar has lectured widely about Artificial Intelligence. He has recently lectured in New York at the National Hemophilia Foundation about AI & the Life Sciences. He has also lectured in London in the Royal Boroughs of Kensington & Chelsea and Westminster, in Sunnyvale in Silicon Valley, the National Library of Singapore as well as in Düsseldorf [with invitations extended to Amsterdam, Berlin, Cologne, Rome, Stockholm & Vienna] on AI and its implications for individuals and societies. Vicar has lectured at leading companies, as well. In April 2022, Vicar will be lecturing at Cambridge Library adjacent to Harvard Square.
Vicar is most interested in the big questions facing humankind. He is particularly focused on studying at the confluence of the five great disciplines of Human History, Political Science and Thought, International Affairs, Science and Technology. For geopolitical technologists, the symbiosis at this intersection offers a deep understanding and pedagogically important lessons of how advances in human endeavor have influenced and impacted civilization.
Vicar has been writing books, essays and poetry for many years. For the past 30 years, Vicar has worked in the Technology and Pharmaceutical industries. He is currently a Consultant in the Life Sciences Industry and lives in suburban Chicago with his wife and their three grown children.
You can find Vicar’s recent book on AI, The Génome Affair on Amazon at this link:
https://www.amazon.com/dp/B07YQ7M9Q7
The most recent episodes of Vicar’s ai & u! Podcast are on YouTube at the following links:
Episode 1 - https://youtu.be/yNYr28jtY_k
What is Artificial Intelligence? What is Human Intelligence?
Episode 2 - https://youtu.be/kAEgDNh1Nwc
How Did We Get Here? Machine Learning, Neural Networks & the AI Lexicon, Exciting AI Agents
Episode 3 - https://youtu.be/3PYCyv1pCgM
Deep Mind - How Powerful is Narrow AI? State Surveillance and Surveillance Capitalism
Episode 4 - https://youtu.be/WvobCMIM_H4
Impact on Societies That Possess Artificial Intelligence Versus Those that Do Not!
Episode 5 - https://youtu.be/4JVpvm4g79g
Surveillance Capitalism, Surveillance State, 4th Industrial Revolution, Bifurcation of Sapiens
Episode 6 - https://youtu.be/e1q2GgcWQok
AI, Blockchain & Quantum Computing - Implications for Global and National Governance
Episode 7 - https://youtu.be/4bDSUvrOdd4
Popular Perceptions of Intelligence, the Seat of Human Intelligence and Implications for AI
Episode 8 - https://youtu.be/3GjHqQZL7Pk
AI - Why Should I care? Plus Exciting Updates from Elon Musk and Neuralink!
Episode 9 - https://youtu.be/enpecqDecC8
AI - Excellence, Innovation & Genius
Episode 10 - https://youtu.be/UsriESlTjdA
Implications for AI as China and the West Decouple
Episode 11 - https://youtu.be/0CpaMb-yw3g
Artificial Intelligence: Ethics, Law & Society
Episode 12 - https://youtu.be/PLzodrLWMq0
AI & Lethal Autonomous Weapons Systems
Episode 13 - https://youtu.be/Lm_nrNyJRbA
AI & the Future of Work in Industry 4.0 – the 4th Industrial Revolution
Episode 14 - https://youtu.be/_3E1Mhr_Dt8
Artificial Intelligence and its Implications for Authoritarianism and Democracy
Episode 15 - https://youtu.be/IpMUqHOEd7w
Artificial Intelligence, Consciousness & the Future of Homo Sapiens
Episode 16 - https://youtu.be/mIf7_VMzGKo
AI and its Implications for America's Political Environment
Episode 17 - https://youtu.be/gsMRPnovZGI
Special Episode: Reading From The Génome Affair
Episode 18 - https://youtu.be/UxNxtWDCREM
Artificial Intelligence - Digital Tyranny, Datocracy and the Imitation Game
Episode 19 - https://youtu.be/Db8U0QQWWuY
Does Artificial Intelligence Really Replicate Human Intelligence?
Episode 20 - https://youtu.be/Np18AEq-6DM
AI & Rising Geopolitical Tensions Between China & The West
Episode 21 - https://youtu.be/fOMSvNiixA0
AI & In-vitro Fertilization [IVF]
Episode 22 - https://youtu.be/EQPpRhIV6Kw
AI & Human Intelligence: A Complex Relationship
Episode 23 - https://youtu.be/EAbQ7stY7JQ
AI Upends the World of Structural Biology
Episode 24 - https://youtu.be/Bsb1F8uoBpA
AI & COVID-19: An Extraordinary Contribution
Episode 25 - https://youtu.be/PqL5PCRc8tA
AI, Connectomics & Transhumanism: the Future of Humankind
Episode 26 - https://youtu.be/HI8Zjl8VM8U
Dramatic Upheaval Inside Google's Ethical AI Team
Episode 27 - https://youtu.be/TqWwJYc2GxQ
AI & Cyber Espionage | How Will the Sunburst Attack Affect Our Security?
Episode 28 - https://youtu.be/89BcThqgcfQ
AI & the Rapidly Escalating Threat from Deep Fake Videos
Episode 29 - https://youtu.be/zvOHRMmJNB4
AI, Facial Recognition Technology & The Digital Surveillance State
Episode 30 - https://youtu.be/br4ygfEWdk0
AI & Social Media | The Most Destructive AI We've Ever Seen?
Episode 31 - https://youtu.be/sOy12ii8zwM
The Democratization of AI & The 2021 Maiflower Expedition | Plymouth, England to Plymouth, MA
Episode 32 - https://youtu.be/bixdLL74reE
Sino-American Cold War | A Blessing in Disguise for America?
Episode 33 - https://youtu.be/tTRm312DgMc
AI & the Tyranny of Meritocracy
Episode 34 - https://youtu.be/FpPzC5VP6GM
In the Midst of Chaos and Pandemic | A Big AI Announcement From the Trump Administration
Episode 35 - https://youtu.be/bK3xCBwrG8w
Artificial Super Intelligence – Can We Control It?
Episode 36 - https://youtu.be/Rc60DQ0L86Q
A New America | Hope with a Big Dose of Caution
Episode 37 - https://youtu.be/UBenYYHbYqM
Will AI [Science & Tech] Benefit From a New Cold War with China?
Episode 38 - https://youtu.be/JewJnPywnOU
Will AI Eventually Replace All Other Forms of Government?
Episode 39 - https://youtu.be/ibuJ8vozyqg
Will AI Perpetuate Bias in Employment, Health Systems, Law and Society?
Episode 40 - https://youtu.be/IJYbPfGC-08
AI | Will it be the Bain of Cyber Criminals?
Episode 41 - https://youtu.be/ozrO5_XTYKQ
AI | What Will it Mean for the Future of Work?
Episode 42 - https://youtu.be/kDKapDK-Vb0
AI | A Harbinger for the End of Democracy?
Episode 43 - https://youtu.be/7XeNyE8CA9I
AI & the Life Sciences | Developments in Connectomics & Radiology
Episode 44 - https://youtu.be/mWaPW_UolVo
AI & Geopolitics | Critical Strategic Planning in the Age of China
Episode 45 - https://youtu.be/qOSOc3vJRBk
AI & Humankind | What Might the Future Hold?
Episode 46 - https://youtu.be/atMSV1WAFkg
AI Enabled Surveillance | An Important Tool to Contain Dangerous Personality Traits?
Episode 47 - https://youtu.be/kz7-EDmlGXc
Will AI Favor Authoritarianism or Democracy?
Episode 48 - https://youtu.be/uTvKWQgdOaI
AI | A Key Enabler of Universal Basic Income?
Episode 49 - https://youtu.be/sy48Xqo-3qM
AI & The Future of Government, Industry, Markets &Trade
Episode 50 - https://youtu.be/JU1oGzb5TS0
AI & Surveillance | America’s New Strategy in the Middle East
Episode 51 - https://youtu.be/nOCQjUxLWJY
AI-Enabled Global Government | An Idea Whose Time Has Come?
Episode 52 - https://youtu.be/g1VJqiI3HyE
AI & Healthcare | What Will the Future Look Like? Will it be More Equitable?
Episode 53 - https://youtu.be/ie9KAg_kF7Q
AI & Surveillance | The Ethical Dilemma of Facial Recognition Software
Episode 54 - https://youtu.be/ie9KAg_kF7Q
AI & Regulation | Europe is Leading the Way
Episode 55 - https://youtu.be/l-gcYTZMsm8
AI & Consciousness | Will Machines Soon be Sentient?
Episode 56 - https://youtu.be/-8BaouCn9cs
AI & Regulation | Europe Announces New Rules
Episode 57 - https://youtu.be/243zm7aHImQ
AI & Human Emotion Recognition | Is it Inherently Flawed?
Episode 58 - https://youtu.be/rdXllGj8rbo
AI & Autonomous Vehicles | Where are We Now?
Episode 59 - https://youtu.be/EMbqpN5mbqw
AI & the 4 Little Trees | More on Emotion Recognition
Episode 60 - https://youtu.be/K5wtkj-VTrk
AI & the Colonial Pipeline Attack | Cyber Threats are Growing Rapidly
Episode 61 - https://youtu.be/03KysO3VJgI
AI & the Coronavirus | A Postmortem
Episode 62 - https://youtu.be/7wmSIWgbuQI
AI on the Battlefield | The Conflict in Gaza
Episode 63 - https://youtu.be/a_1AmLJD3lo
AI and Xenophobia | Will We Finally Break the Cycle?
Episode 64 - https://youtu.be/9s-Go1TYK9c
AI, Cyber Attacks & the Future of War | Where are We Headed?
Episode 65 - https://youtu.be/1nKbTMzfpqM
Artificial Intelligence | Humankind’s Final and Greatest Invention
Episode 66 - https://youtu.be/cplR62KTa88
America & the 4th Industrial Revolution | Where do We Go from Here?
Episode 67 - https://youtu.be/RMrqreI-PRw
Artificial Intelligence | [Digital] Life After Death
Episode 68 - https://youtu.be/KzR8NkVdT0Q
Artificial Intelligence | The Fear Factor
Episode 69 - https://youtu.be/BI0HqACc4Ek
Artificial Intelligence | The Trust Factor
Episode 70 - https://youtu.be/nKhqVtQC_NI
Artificial Intelligence | Implications for the Future of Democracy
Episode 71 - https://youtu.be/GKD5hXmnpTU
Artificial Intelligence | Deep Fakes & Pornography
Episode 72 - https://youtu.be/KJdoBm5Kmw8
Artificial Intelligence | Working in the 21st Century
Episode 73 - https://youtu.be/lLY6gF_eeas
AI & Disinformation | Implications for Democracy & Geopolitics
Episode 74 - https://youtu.be/URsauWURj5A
AI, Climate Change & Pandemics | A Case for Global Governance?
Episode 75 - https://youtu.be/cu7xOHpNiO4
Artificial Intelligence | New Year’s Resolutions & Societal Reformation
Episode 76 - https://youtu.be/1-orEsKg5fM
Artificial Intelligence | Meritocracy and the Gathering Storm
Episode 77 - https://youtu.be/jYzyrxhxCJk
AI, Authoritarianism & Democracy | What Does the Future Hold?
Episode 78 – https://youtu.be/G5dlaB8TZJQ
AI & Speciation | Symbiosis and the 4th Industrial Revolution
Episode 79 – https://youtu.be/8pq2ZAxRdcY
AI and Disinformation | Echo Chambers in an Age of Division
Episode 80 – https://youtu.be/bewLnveVpDI
AI & Human Conflict | Objectivism, Tribalism & the Dunning-Kruger Effect
Episode 81 – https://youtu.be/Z5ZvMYuNhLQ
AI, Climate Change & Migration | Sowing the Seeds of Intraplanetary Discord
Episode 82 – https://youtu.be/mP-r_0pS3P8
Artificial Intelligence in 2022 | Where are We Now and What Does the Future Hold?
Episode 83 – https://youtu.be/vYSW-pceOQE
Artificial Intelligence in 2022 | Is Protein Folding Our Most Important Achievement?
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