Researchers: First animal cell was not simple; it could “transdifferentiate”

structure of an animal cell/royroydeb (CC BY-SA 4.0)

From Nature: “Transdifferentiation is the conversion of a cell type present in one tissue or organ into a cell type from another tissue or organ without going through a pluripotent cell state. Transdifferentiation between some cell types can occur naturally in response to injury and can be induced experimentally.”

From the abstract of an interesting preprint:

… these analyses offer no support for the homology of sponge choanocytes and choanoflagellates, nor for the view that the first multicellular animals were simple balls of cells with limited capacity to differentiate. Instead, our results are consistent with the first animal cell being able to transition between multiple states in a manner similar to modern transdifferentiating and stem cells.Shunsuke Sogabe, William L. Hatleberg, Kevin M. Kocot, Tahsha E. Say, Daniel Stoupin, Kathrein E. Roper, Selene L. Fernandez-Valverde, Sandie M. Degnan and Bernard M. Degnan, “Pluripotency and the origin of animal multicellularity” at bioarxiv

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Before you go: “Interspecies communication” strategy between gut bacteria and mammalian hosts’ genes described

Researchers: Cells Have A Repair Crew That Fixes Local Leaks

Researchers: How The Immune System “Thinks”

Researcher: Mathematics Sheds Light On “Unfathomably Complex” Cellular Thinking

How do cells in the body know where they are supposed to be?

Researchers A Kill Cancer Code Is Embedded in Every Cell

How Do Cells Interpret The “Dizzying” Communications Pathways In Multicellular Life Forms?

and

Cell atlases reveal extreme complexity at biology’s frontiers

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