Fasting and AMPk Signaling – Lean vs. Obese

Introduction AMPk is a cellular energy sensor, activated mostly at low energy states. Its activation often depends on ratios such as AMP/ATP and NAD+/NADH. The main purpose of AMPk activation is to restore cellular energy. “Thus, any change in cellular energy status activates AMPK, leading to concomitant inhibition of energy-consuming processes and stimulation of ATP-generating