My last SFF read was SPACE OPERA by Catherine Valente (literally space opera). It was like having a drunk, very dynamic discussion with someone I vehemently disagree with. Well-written, and actually influenced my thinking about some points (although as a sexual health physician I was very "no way" about the high-risk sexual promiscuity). Very beautiful discussion of the pain of being an immigrant in a country that doesn't want you (I'm the mixed-race child of immigrants who DID feel wanted, so the difference in experience matters to me).
I just finished "The Enclave," by Karen Hancock, LOVE that book, re-read it again after many years and it still holds up. I love the science gone awry, combined with "Man playing God"/Nephilim aspects of that title. HIGHLY recommended.
What about you guys?