YA books with a unique concept, depressing at times, and LGBT character(s)?

[Regina]

I read Before I Fall, and Thirteen reasons why, perks of being a wallflower, etc. anyone know of any others

[Rosa]

The Best Night of Your (Pathetic) Life
Aristotle and Dante Discover the Secrets of the Universe

[J.S.]

Suicide Watch & Made of Stars by Kelley York.

How to Repair a Mechanical Heart by JC Lillis (which isn't so much depressing as it is extremely awesome).

[Zombieslayer⚡Alienhunter]

These recs are all sci-fi. Ignore if that isn't for you. The interesting concept/depressing at times labels definitely apply, though.

Proxy
Coda
More Happy Than Not
Grasshopper Jungle

[Julie]

The Serpent King
The Inexplicable Logic of My Life
They Both Die at the End

[[deleted user]]

Fat Angie fits the criteria to the letter and is one of the best books I have ever read.

[Rosa]

Fat Angie for Andy's suggestion.
The Secret of a Heart Note

[Mandy]

All the Bright Places (I can't remember if it has LGBTI characters but it is very good).

[[deleted user]]

We Are the Ants
Love Is the Higher Law
This Is Where It Ends
Forgive Me, Leonard Peacock

[Rainbowheart]

My Heartbeat
Someday This Pain Will Be Useful to You

[The Reading Raccoon]

I'll Give You the Sun

[Andria]

The Wicker King

[Julia]

Will Grayson, Will Grayson by John Green is really funny!

[Rainbowheart]

Suicide Notes

[Laura]

Leave Myself Behind

Tell the Wolves I'm Home

[Rainbowheart]

Darius the Great Is Not Okay

[The Reading Raccoon]

Violent Ends

[SamSpayedPI]

Surprised no one has mentioned Call Me By Your Name.

[Serena]

miles away from you by ab Rutledge

fire song by adam garnet jones

I was here by gayle forman is good if you liked 13 reasons why but its about female friendship not a romance

[Rainbowheart]

The Dangerous Art of Blending In

[River]

The Last 8

[Rainbowheart]

The Drowning of Stephan Jones

[Astra]

A Cosmology of Monsters by Shaun Hamill
The Strange Fascinations of Noah Hypnotik by David Arnold