But others disagreed. With screening tests still faltering, with carcinogens still at large, and with the mechanistic understanding of cancer in its infancy, the impatience to deploy a large-scale therapeutic attack on cancer grew to its bristling tipping point. A chemotherapeutic was a poison, and one did not need to understand a cancer cell to poison it. So, just as a generation of radical surgeons had once shuttered the blinds around itself and pushed the discipline to its terrifying limits, so, too, did a generation of radical chemotherapists. If every dividing cell in the body needed to
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