If that is really the case, then a novel clinical intervention should work: take one of those depressives with high glucocorticoid levels, find some drug that works on the adrenals to lower glucocorticoid secretion, and the depression should lessen. And, very exciting, that has been shown. The approach, though, is filled with problems. You don’t want to suppress glucocorticoid levels too much because, umpteen pages into this book, it should be apparent by now that those hormones are pretty important. Moreover, the “adrenal steroidogenesis inhibitors,” as those drugs are called, can have some
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