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IBS—also known as “spastic colon”—involves the colon being too contractile, an excellent way of producing diarrhea. (It is not clear why lots of stress-induced contractions of the colon can lead to constipation. As a possible explanation, the stress-induced contractions in the colon are directional, which is to say, they push the contents of the colon from the small intestinal end to the anus. And if they do that a lot, things get accelerated, resulting in diarrhea. However, in one plausible scenario, with long enough periods of stress, the contractions begin to get disorganized, lose their ...more
Why Zebras Don't Get Ulcers: The Acclaimed Guide to Stress, Stress-Related Diseases, and Coping
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