But tear it loose now, form what is called a thrombus, and that mobile hairball can now lodge in a much smaller blood vessel, clogging it completely. Clog up a coronary artery and you’ve got a myocardial infarct, a heart attack (and this thrombus route accounts for the vast majority of heart attacks). Clog up a blood vessel in the brain and you have a brain infarct (a stroke).