sufferers have abnormally high levels of activity in parts of the brain that mediate the emotional/contextual assessments of pain, the same areas activated in stress-induced hyperalgesia. Moreover, their cerebral spinal fluid contains elevated levels of a neurotransmitter that mediates pain (called Substance P). And, as noted in chapter 2, unexpectedly, glucocorticoid levels are below normal in people with fibromyalgia.
