we cannot doubt but the severity of those Confinements, made many People desperate; and made them run out of their Houses at all Hazards, and with the Plague visibly upon them, not knowing either whither to go, or what to do, or indeed, what they did; and many that did so, were driven to dreadful Exigences and Extremeties, and Perish’d in the Streets or Fields for meer Want, or drop’d down, by the raging violence of the Fever upon them: