Sweden to discover that normal human cells have forty-six chromosomes. Once scientists knew how many chromosomes people were supposed to have, they could tell when a person had too many or too few, which made it possible to diagnose genetic diseases. Researchers worldwide would soon begin identifying chromosomal disorders, discovering that patients with Down syndrome had an extra chromosome number 21, patients with Klinefelter syndrome had an extra sex chromosome, and those with Turner syndrome lacked all or part of one.