Lisa Eirene

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people who weren’t killed by infectious diseases died from famine, as crops rotted in the fields because there was no one to harvest them. The malnourished survivors were susceptible to whatever pathogens would arrive next from Spain. The scale of the cumulative devastation is hard to imagine: the indigenous population of Mesoamerica was about 20 million when Cortés arrived but had fallen to 1.5 million a century later.
Pathogenesis: A History of the World in Eight Plagues
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