In the south, agricultural workers who hadn’t developed immunity to falciparum malaria were likely to get very sick. As a result, European indentured laborers were no longer wanted, and nor did they want to settle there.[60] From an amoral economic perspective, West African labor suddenly became a much more appealing proposition for plantation owners. The Italian economist Elena Esposito estimates that the arrival of falciparum malaria in the 1680s explains the rapid rise in numbers of African Americans in the southern colonies from that time—a conclusion that holds even when other possible
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