Science of Neuro-Associative Conditioning™, or NAC. What is it? NAC is a step-by-step process that can condition your nervous system to associate pleasure to those things you want to continuously move toward and pain to those things you need to avoid in order to succeed consistently in your life without constant effort or willpower. Remember, it’s the feelings that we’ve been conditioned to associate in our nervous systems—our neuro-associations—that determine our emotions and our behavior.