AUTOIMMUNE HEMOLYTIC ANEMIA Autoantibodies against RBC membrane destroy blood cells, causing extravascular hemolysis. Two types: Warm: IgG, associated with SLE, chronic lymphocytic leukemia (CLL), lymphoma, penicillin, rifampin, phenytoin, and α-methyldopa Cold: IgM, associated with Mycoplasma pneumonia, EBV, and Waldenström macroglobulinemia
