longer successfully use insulin as a hormone to escort the sugar from your food into your cells. When your cells become unable to use glucose for fuel, not only will you experience a depletion in energy but they will store the unused glucose as fat. This is the root cause of metabolic syndrome, which is defined as having three out of five of the following components: obesity, high blood pressure, high blood triglycerides, high blood sugar, or low levels of HDL cholesterol.