What factors had contributed to the potential cure? The particular strain of HIV? The low viral load before the transplants? The “engineering” of Brown’s immune system after the transplant? Answers to these questions will guide the next wave of HIV therapies. We will learn about where the virus hides, how to attack its reservoirs, how cells might resist infection. Most importantly, we’ll learn about how the immune system can be taught to recognize this most devious of pathogens.