His normal doses of thyroid medication—enough to increase his hormone levels into the “healthy” range—had done nothing to improve his depression, but we decided to try high-dose thyroid hormone as a treatment. It made a huge difference! His levels of thyroid hormone were now abnormally high, so we had to keep an eye out for side effects, such as heart arrhythmias and osteoporosis. But overall, he tolerated it quite well, and it changed his life. His recurrent depressions were all but gone. After about ten years of treatment with a high-dose of thyroid hormone, he was able to decrease the dose
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