In addition to dampening reward sensitivity, THC acts in pathways that ascribe value or import to our experiences, and if these are muted, especially for a lifetime, the impacts are likely to be broad and deep. The heart of the matter is that the brain adapts to any drug that alters its activity and it appears to do this permanently when exposure occurs during development. The more exposure to the substance we have, and the earlier we have it, the more strongly the brain adjusts.
