The raison d’être for the Krebs cycle is muddied even further by the fact that the cycle supplies many of the basic building blocks for the fabric of the cell. Most amino acids are made directly or indirectly from molecules in the Krebs cycle. So are the long-chain lipid molecules needed to make cell membranes. New sugars are made from the Krebs cycle too. Even the ‘letters’ of DNA (termed nucleotides) are made from sugars and amino acids, and so also derive from the Krebs cycle. I could go on but suffice to say that the Krebs cycle is the engine of biosynthesis, driving cellular growth and
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