His most famous gaffe occurred during an address to the United Negro College Fund, when, just as Bush struggled to retrieve the correct cliché about a half-empty glass, Quayle tried to pry loose from his tangled synapses the organization’s famous slogan, “A mind is a terrible thing to waste”: “You take the United Negro College Fund model that what a waste it is to lose one’s mind or not to have a mind is being very wasteful. How true that is.”
