The global spice trade underwent an upheaval in 1453, when Constantinople fell to the Turks, and the time-honored overland spice routes between Asia and Europe were severed. The prospect of establishing a spice trade via an ocean route opened up new economic possibilities for any European nation able to master the seas. For those willing to assume the risks, the rewards of an oceanic spice trade, combined with control over the world’s economy, were irresistible.