The sympathetic nervous system, or the fight-or-flight system, is activated by stress. This is the system that gets us ready to run. The counter to this is the parasympathetic nervous system, the resting-and-digesting system. It lowers heart rate and blood pressure, slows breathing, and directly counters the stress response. Meditation activates the parasympathetic nervous system.[3] It’s literally the antidote to stress.