Calculating the baseline, the average population-wide or sex- and age-specific risk of overall mortality, is easy. In 2019, overall mortality (crude death rate) of well-off (developed) countries clustered at around 10/1,000, with actual rates ranging from 8.7 for North America to 10.7 in Japan and 11.1 for Europe. That annual mortality of 10/1,000 (with 1,000 people subject to dying for 8,766 × 1,000 hours) prorates to 0.000001 or 1 × 10-6 per person per hour of exposure. Cardiovascular diseases are the leading cause of mortality in all affluent countries and they account for nearly a quarter
...more

