Collagen protein supplements and type II collagen supplements are both good for your joints, but they have different mechanisms of action. Collagen protein benefits your joints by kick-starting collagen production and supplying the building blocks of healthy joints. Type II collagen supplements have a novel “oral vaccine” effect that builds immune cell tolerance, reduces autoimmune reactions, and relieves inflammation-based pain.162 Think of collagen protein as a joint builder and type II collagen as an anti-inflammatory pain reliever.

