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Not till we are lost, in other words, not till we have lost the world, do we begin to find ourselves, and realize where we are and the infinite extent of our relations.
Asante
Kumasi,
Ghana.
I vaguely remembered a childhood kindness, but maybe I was conflating innocence and kindness. I felt so little continuity between who I was as a young child and who I was now that it seemed pointless to even consider showing my mother something like mercy. Would I have been merciful when I was a child?
Though I had done this millions of times, it still awed me to see a brain. To know that if I could only understand this little organ inside this one tiny mouse, that understanding still wouldn’t speak to the full intricacy of the comparable organ inside my own head. And yet I had to try to understand, to extrapolate from that limited understanding in order to apply it to those of us who made up the species Homo sapiens, the most complex animal, the only animal who believed he had transcended his Kingdom, as one of my high school biology teachers used to say. That belief, that transcendence,
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That’s what the worship leader’s voice sounded like to me—the shaky body of a bird in distress, a child who’d grown suddenly afraid. I checked that career off my list right away.
I should have comforted her, told her it wasn’t her fault, but somewhere, just below the surface of me, I blamed her. I blamed myself too. Guilt and doubt and fear had already settled into my young body like ghosts haunting a house. I trembled, and in the one second it took for the tremble to move through my body, I stopped believing in God. It happened that quickly, a tremble-length reckoning. One minute there was a God with the whole world in his hands; the next minute the world was plummeting, ceaselessly, toward an ever-shifting bottom.
“The truth is we don’t know what we don’t know. We don’t even know the questions we need to ask in order to find out, but when we learn one tiny little thing, a dim light comes on in a dark hallway, and suddenly a new question appears. We spend decades, centuries, millennia, trying to answer that one question so that another dim light will come on. That’s science, but that’s also everything else, isn’t it? Try. Experiment. Ask a ton of questions.”
The two of us back then, mother and daughter, we were ourselves an experiment. The question was, and has remained: Are we going to be okay?
Ama Ata Aidoo’s book Changes, in which the character Esi says, “you cannot go around claiming that an idea or an item was imported into a given society unless you could also conclude that to the best of your knowledge, there is not, and never was any word or phrase in that society’s indigenous language which describes that idea or item.”
I wanted to flay any mental weakness off my body like fascia from muscle.
By that time my mother had already “healed through prayer,” as Pastor John put it. Healed, but in the way a broken bone that’s healed still aches at the first signs of rain. There were always first signs of rain, atmospheric, quiet. She was always aching. She would come visit me when I was in undergrad at Harvard, bundled up against the winter, even if it was spring. I’d look at her coat, her head scarf wrapped tight, and wonder when I had stopped thinking of her as a strong woman. Surely, there’s strength in being dressed for a storm, even when there’s no storm in sight?
I had studied her face for any sign of collapse, trying to make myself an expert on the shades of sadness I recognized in her eyes. Was it lurking there again, the dark, deep sadness, or was it just the everyday kind, the kind we all have from time to time, the kind that comes and, more important, goes? It had been almost three days since I’d seen my mother’s face, but I had studied her enough to know which kind of sadness I would find there.
I think that I remember that day, but I don’t know if I’ve just turned my mother’s stories about it into memories or if I’ve stared at that picture long enough that my own stories started to emerge.
But the memory lingered, the lesson I have never quite been able to shake: that I would always have something to prove and that nothing but blazing brilliance would be enough to prove it.
King Lear. We are not ourselves when nature, being oppressed, commands the mind to suffer with the body.
My pray-without-ceasing experiment had all but proven the impossibility of controlling my thoughts. I could control one layer, the most readily available layer, but there was always a sublayer lurking. That sublayer was truer, more immediate, more essential, than anything else. It spoke softly but constantly, and the things it said were the very things that allowed me to live and to be. Now I understand that we have a subconscious life, vibrant and vital, that acts in spite of “ourselves,” our conscious selves.
I am looking for new names for old feelings. My soul is still my soul, even if I rarely call it that.
Nana had tears in the corners of his eyes that were threatening to spill, and he was making a face that I’ve only ever seen in young boys, a face that is the façade of a man, hiding a boy who has had to grow up far too fast. I have seen that faux tough look on boys as they pushed shopping carts, walked siblings to school, bought cigarettes for their parents who waited in their cars. It breaks my heart now, to see that face, to recognize the lie of masculinity sitting atop the shoulders of a young child.
Dear God, Buzz says that Christianity is a cult except that it started so long ago that people didn’t know what cults were yet. He said we’re smarter now than we were back then. Is that true?
My guess is that it wasn’t just Nana’s body that couldn’t sit still. He had a mind that was always thrumming. He was curious, intense, often quiet, and when he asked a question there were a hundred more lurking behind it. This constant striving for exactness, the right position for his legs, the right thing to say, was what made him someone who could shoot free throws for hours on end, but it also made him someone who had a harder time changing the narrative—getting from a negative self-statement to a positive one. When he said, “I don’t give a fuck what he thinks,” he said it in such a way
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“What’s the point of all of this?” is a question that separates humans from other animals. Our curiosity around this issue has sparked everything from science to literature to philosophy to religion. When the answer to this question is “Because God deemed it so,” we might feel comforted. But what if the answer to this question is “I don’t know,” or worse still, “Nothing”?
When you’re that young, time already seems to crawl. The distance between ages four and five is forever. The distance between the present and the biblical past is unfathomable. If time was real, then anything at all could be real too.
I mean progress in the sense of the natural way in which learning something new requires getting rid of something old, like how discovering that the world is round means that you can no longer hang on to the idea that you might one day fall off the edge of the Earth. And now that you have learned that something you thought was true was never true at all, every idea that you hold firm comes into question. If the Earth is round, then is God real? Literalism is helpful in the fight against change.
Most of the time in my work, I begin with the answers, with an idea of the results. I suspect that something is true and then I work toward that suspicion, experimenting, tinkering, until I find what I am looking for. The ending, the answer, is never the hard part. The hard part is trying to figure out what the question is, trying to ask something interesting enough, different enough from what has already been asked, trying to make it all matter. But how do you know when you are nearing a true end instead of a dead end? How do you finish the experiment? What do you do when, years into your
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Before long, Pastor John took the microphone and went up to the makeshift pulpit at the front of the room in order to say a word. “We know that Nana was a talented young man. Many of us in this room saw him on the basketball court, shooting that basketball toward the Heavens themselves. It brought us joy to watch him and to recognize in this young man the glory of the Lord. Now whenever a young person dies, it’s easy for those of us who were left behind to get angry. We think, why would God do this? Nana had so much to give, God, why? It’s normal to feel that way, but let me remind you, God
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In Philosophical Foundations of Neuroscience, Bennett and Hacker write: What [neuroscience] cannot do is replace the wide range of ordinary psychological explanations of human activities in terms of reasons, intentions, purposes, goals, values, rules and conventions by neurological explanations…For it makes no sense to ascribe such psychological attributes to anything less than the animal as a whole. It is the animal that perceives, not parts of its brain, and it is human beings who think and reason, not their brains. The brain and its activities make it possible for us—not for it—to perceive
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“I know that psychology and neuroscience have to work in concert if we want to address the full range of human behavior, and I really do love the idea of the whole animal, but I guess my question is that if the brain can’t account for things like reason and emotion, then what can? If the brain makes it possible for ‘us’ to feel and think, then what is ‘us’? Do you believe in souls?”
“Anhedonia” is the psychiatric term for the inability to derive pleasure from things that are normally pleasurable. It’s the characterizing symptom in major depressive disorder, but it can also be a symptom of substance abuse, schizophrenia, Parkinson’s disease. I learned the term in a university lecture hall and immediately felt a shock of recognition. Anhedonia was the feeling of “nothing,” the thing that kept my mother in her bed.
And that’s what so many people want to get at: the cause of the drug use, the reason people pick up substances in the first place. Anytime I talk about my work informally, I inevitably encounter someone who wants to know why addicts become addicts. They use words like “will” and “choice,” and they end by saying, “Don’t you think there’s more to it than the brain?” They are skeptical of the rhetoric of addiction as disease, something akin to high blood pressure or diabetes, and I get that.
What they’re really saying is that they may have partied in high school and college but look at them now. Look how strong-willed they are, how many good choices they’ve made. They want reassurances. They want to believe that they have been loved enough and have raised their children well enough that the things that I research will never, ever touch their own lives.
I understand this impulse. I, too, have spent years creating my little moat of good deeds in an attempt to protect the castle of myself. I don’t want to be dismissed the way that Nana was once dismissed. I know that it’s easier to say Their kind does seem to have a taste for drugs, easier to write all addicts off as bad and weak-willed people, than it is to look closely at the nature of their suffering. I do it too, sometimes. I judge. I walk around with my chest puffed out, making sure that everyone knows about my Harvard and Stanford degrees, as if those things encapsulate me, and when I do
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Forget for a moment what he looked like on paper, and instead see him as he was in all of his glory, in all of his beauty. It’s true that for years before he died, I would look at his face and think, What a pity, what a waste. But the waste was my own, the waste was what I missed out on whenever I looked at him and saw just his addiction.
My mother crawled out of her deep, dark tunnel, but perhaps this phrasing is too imprecise, the image of crawling too forceful to encapsulate the relentless but quiet work of fighting depression. Perhaps it is more correct to say that her darkness lifted, the tunnel shallowed, so that it felt as though her problems were on the surface of the Earth again, not down in its molten core.
Who was she then, I wondered, as Mrs. Palmer’s children and grandchildren folded my mother into their arms. My mother—who had never hugged us, even when we were little children presenting her with our scrapes and bruises, our wails—accepted the touch of these strangers, who, of course, weren’t strange to her. She spent more of her days with Mrs. Palmer than she had ever spent with us. And so I recognized, for perhaps the first time, that my mother wasn’t mine.
I understood that the same thing that made humans great—our recklessness and creativity and curiosity—was also the thing that hampered the lives of everything around us. Because we were the animal daring enough to take boats out to sea, even when we thought the world was flat and that our boats would fall off the edge, we discovered new land, different people, roundness. The cost of this discovery was the destruction of that new land, those different people. Without us oceans wouldn’t be turning to acid, frogs and bats and bees and reefs wouldn’t be heading for extinction. Without me, the
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I couldn’t imagine living the way she lived, free, like an exposed wire ready and willing to touch whatever it touched. I couldn’t imagine being willing, and even after those few stolen moments of psychedelic transcendence, nonaddictive, harmless, and, yes, euphoric, I still couldn’t imagine being free.
it wasn’t fair. That was the thing that was at the heart of my reluctance and my resentment. Some people make it out of their stories unscathed, thriving. Some people don’t.
It was hard to fight sleep, and the television, at that volume, did little to help. I’d doze off in the recliner and the nightmare would shoot me upright, awake with panic. I started praying feverishly. I would ask God to stop the dreams, and if he wouldn’t stop the dreams, I would ask that he’d at least allow me to remember them. I couldn’t stand not knowing what I was afraid of.

