The flood of activating signals wakes up immune cells all over the body, who then might release more. Inflammation rises massively and is no longer limited just to the place of infection. Immune cells flood the affected organs and can cause profound damage. Blood vessels all over the body get leaky and fluid rushes into the tissue and out of the vascular system. In the worst case, the blood pressure will fall to critical levels, and organs will not receive enough oxygen and begin to shut down, which can end deadly.
