So, given the downsides of most non-alcoholic chemical intoxicants, and the incredible amount of time, effort, and pain demanded by non-chemical means, it’s not surprising that most of us, most of the time, have chosen to opt for a few pints of beer over sticking sharp objects through our cheeks. If we want to enhance mood and temporarily take the PFC offline, a delicious liquid neurotoxin seems to be the fastest and most pleasant option.