Depo-Provera is a powerful poison, with a devastating inventory of wretched side effects: Under federal law, the Depo-Provera label must bear FDA’s most stringent Black Box warning—due to its potential to cause fatal bone loss. Furthermore, women have reported both missed periods and excessive bleeding; blood clots in arms, legs, lungs, and eyes; stroke; weight gain; ectopic pregnancy; depression; hair loss; decreased libido; and permanent infertility.

