We have devices to replace our hips, knees, shoulders, elbows, wrists, jaws, teeth, skin, arteries, veins, heart valves, arms, legs, feet, fingers, and toes, and systems to replace more complex organs (for example, our hearts) are beginning to be introduced. As we learn the operating principles of the human body and brain, we will soon be in a position to design vastly superior systems that will last longer and perform better, without susceptibility to breakdown, disease, and aging.