And finally, the cross-sex hormones to which early social transitioning almost inevitably leads come with their own risks. For transmen, they are associated with higher risks of cardiovascular problems, including high blood pressure, heart attacks and stroke, dementia in later life, liver problems, diabetes and joint problems. Less is known about the impact on transwomen, but low testosterone is known to cause fatigue, brittle bones and high cholesterol levels in biological males, and taking oestrogen is likely to raise their risk of some cancers, including breast cancer.
