Since the completion of the Human Genome Project in 2003, the cost of genome sequencing has followed a sustained exponential trend, falling on average by around half each year. Despite a brief plateau in sequencing costs from 2016 to 2018 and slowed progress amid the disruptions of the COVID-19 pandemic, costs continue to fall—and this will likely accelerate again as sophisticated AI plays a greater role in sequencing. Costs have plunged from about $50 million per genome in 2003 to as low as $399 in early 2023, with one company promising to have $100 tests available by the time you read
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