As de Grey explains, aging is like the wear on the engine of an automobile—it is damage that accumulates as a result of the system’s normal operation. In the human body’s case, that damage largely comes from a combination of cellular metabolism (using energy to stay alive) and cellular reproduction (mechanisms for self-replication). Metabolism creates waste in and around cells and damages structures through oxidation (much like the rusting of a car!). When we’re young, our bodies are able to remove this waste and repair the damage efficiently. But as we get older, most of our cells reproduce
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