When a sixteen-year-old female epileptic patient was undergoing brain surgery in the late 1990s, the neurosurgeon Itzhak Fried kept her awake so she could respond to what was happening.[58] This was feasible because there are no pain receptors in the brain.[59] Whenever he stimulated a particular spot on her neocortex, she would laugh. Fried and his team quickly realized that they were triggering the actual perception of humor. She was not just laughing as a reflex—she genuinely found the present situation funny, even though nothing humorous had occurred in the operating room. When the doctors
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