The Dendritic Cells of your gut behave in a special way too. Many of them sit directly below the layer of epithelial cells and squeeze their long arms between them, reaching right into the mucus of the gut. This way they can constantly sample the bacteria that are cheeky enough to not stay in their lane but venture too deep. At this point lies a huge mystery of immunology that promises another Nobel Prize for the person or team who solve it one day: How do Dendritic Cells know if the bacteria they sample in the gut are dangerous pathogens or just harmless commensal bacteria? Well, right now we
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