Dan Seitz

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This is not to say that all of these increases are due to better hygiene, a drop in childhood infection, and its association with wealth and education. There have been many changes to our environment, including new pollutants. There are absolutely genetic factors as well. But the hygiene hypothesis—and when it comes to allergy, the inverse relationship between industrialized processes and health—prevails.
An Elegant Defense: The Extraordinary New Science of the Immune System: A Tale in Four Lives
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