Dan Seitz

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In other words, the immune system was more deliberate the first time around in rejecting a sibling’s tissue, but once the skin was determined to be “alien,” the rejection came more quickly. This underscored the ability of the immune system to learn; the first time the elegant defense took a while to assess the skin as foreign and build the machinery to reject it, but the second time, with the machinery in place, judgment was fast and merciless.
An Elegant Defense: The Extraordinary New Science of the Immune System: A Tale in Four Lives
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