According to quantum mechanics, trajectories become jittery, blurry, and poorly defined at the microscopic scale, so we need to describe the behavior of electrons as probability waves instead of Newtonian trajectories. As soon as we do that, however, calculus returns triumphantly. It governs the evolution of probability waves through something called the Schrödinger equation. It’s incredible but true: Even in the subatomic realm where Newtonian physics breaks down, Newtonian calculus still works.