The more inaccurate the information your PFC incorporates, the worse the outcome. And as the scenarios become more worst-case (which tends to happen as the PFC starts to go off-line, ironically due to the ramping up of the anxiety), your fight/flight/freeze physiology can get triggered to the point that just thinking about these possible (but highly improbable) situations can make you feel that you’re in danger, even though the danger is only in your head. Voilà! Anxiety.