Arthur Sackler rarely spoke about the toll of addiction and abuse associated with the tranquilizers that made him rich. But when he did, he made a telling distinction. People did abuse these drugs, Arthur conceded. But the real explanation for this phenomenon was not any intrinsically addictive properties of the drugs themselves. Rather, it was a reflection of the addictive personalities of the users. As evidence emerged that OxyContin was being abused, Richard Sackler adopted a similar view.