But then I learned that too many endotoxins—the outer layer of bacteria—could be responsible for some of these feelings of fogginess. Gram-negative bacteria, the most common type in the world, can be found in your gut, and their cell walls contain lipopolysaccharide (LPS), which is an endotoxin and one of the most potent inflammatory substances known to man. When you have an overgrowth of bacteria in your small intestine (SIBO), and those bacteria die (either through treatment or on their own), they release their LPS.
