There’s a growing body of literature that shows adverse childhood experiences lead to many negative health outcomes by triggering a dysregulated stress response that affects the developing brain as well as the endocrine and immune systems. This is known as the toxic stress response, and it can have profoundly negative complications. Exposure to four or more adverse childhood experiences increases the risk of many conditions intertwined with menopause such as heart attack, stroke, sleep disorders, Alzheimer’s disease, diabetes, depression, and breast cancer. Trauma literally rewires the brain
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