In 1309 the popes began their exile at Avignon. In 1339 the Hundred Years War was begun between England and France. Increasing famines and plague culminated in the Black Death of 1348–1349. The Jacquerie, the French peasant insurrection, took place in 1358 and the Great Ecclesiastical Schism lasted from 1378 to 1417. There were risings in England and France in 1381–1382 and the Habsburgs were defeated by the Swiss Confederation four years later. In 1395 the Turks destroyed the Hungarian army at Nikopolis, the beginning of a campaign that culminated in 1453 with the fall of Constantinople.

