Ashwagandha. Animal studies find that ashwagandha has immunomodulatory effects by upregulating Th1 and macrophages[1887],[1888]. In humans, ashwagandha has been shown to reduce stress and balance the immune system[1889],[1890]. Amongst 5 people, ashwagandha upregulated the expression of CD4 and CD3+ T cells 96 hours after consumption[1891].
