She is confident that the good that can come from CRISPR will eventually outweigh the dangers. “Science doesn’t move backwards, and we can’t unlearn this knowledge, so we need to find a prudent path forward,” she says, reprising the phrase in the title of the report she wrote after her 2015 Napa Valley meeting. “We’ve never seen anything like this before. We now have the power to control our genetic future, which is awesome and terrifying. So we must move forward cautiously and with respect for the power we’ve gained.”